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Hypabase vs Neo4j

The core difference

Neo4j is a property graph database. Every edge connects exactly two nodes. When your data has relationships between 3+ entities, Neo4j requires you to decompose them using intermediate nodes (the reification pattern).

Hypabase is a hypergraph library. A single edge connects any number of nodes directly.

Modeling n-ary relationships

The fact: "Dr. Smith treated Patient 123 with Aspirin for Headache at Mercy Hospital"

Neo4j

Neo4j edges connect exactly two nodes. To model a 5-entity relationship, you create an intermediate node:

CREATE (t:Treatment)
CREATE (dr_smith)-[:TREATS]->(t)
CREATE (t)-[:PATIENT]->(patient_123)
CREATE (t)-[:MEDICATION]->(aspirin)
CREATE (t)-[:CONDITION]->(headache)
CREATE (t)-[:LOCATION]->(mercy_hospital)

Hypabase

hb.edge(
    ["dr_smith", "patient_123", "aspirin", "headache", "mercy_hospital"],
    type="treatment",
    source="clinical_records",
    confidence=0.95,
)

Comparison

Neo4j Hypabase
Edge model Binary (2 nodes per edge) N-ary (2+ nodes per edge)
N-ary relationships Reification pattern Native hyperedges
Query language Cypher Python SDK
Provenance Custom properties Built-in source and confidence
Setup Server process or cloud uv add hypabase
Storage Custom binary format SQLite
Visualization Neo4j Browser, Bloom None
Drivers Python, Java, JS, .NET, Go Python only
Data size Disk-backed, scales to billions In-memory, limited by RAM
Concurrency Multi-user, ACID transactions Single-process

When to use Neo4j

  • You have pairwise relationships and Cypher's pattern matching fits your queries
  • You need a declarative query language — Cypher is genuinely powerful for complex graph patterns
  • You need concurrent multi-user access with ACID transactions
  • Your data exceeds available memory
  • You need built-in visualization
  • You want managed cloud deployment (Neo4j Aura)
  • You need non-Python drivers (Java, JS, .NET, Go)

When to use Hypabase

  • Your relationships connect 3+ entities and you want them to stay atomic
  • You need provenance tracking as part of the data model, not an afterthought
  • You want zero-config embedded storage with no server to manage
  • Your data fits in memory and you want fast in-process access
  • You're integrating with AI agents via MCP

Code comparison: patient lookup

Neo4j

MATCH (p:Patient {id: 'patient_123'})-[:PATIENT]-(t:Treatment)
MATCH (t)-[:TREATS]-(d:Doctor)
MATCH (t)-[:MEDICATION]-(m:Medication)
MATCH (t)-[:CONDITION]-(c:Condition)
RETURN d, m, c

Hypabase

edges = hb.edges(containing=["patient_123"], type="treatment")
# Each edge contains all connected entities directly